Physiology
Study Data from University of Manitoba Provide New Insights into Physiology
Published in Gene Therapy Weekly, October 27th, 2011
2011 OCT 27 -- According to the authors of recent research from Winnipeg, Canada, "We investigated the mechanisms responsible for increased blood pressure and sympathetic nerve activity (SNA) caused by 2-3 days dehydration (DH) both in vivo and in situ preparations. In euhydrated (EH) rats, systemic application of the AT(1) receptor antagonist Losartan and subsequent pre-collicular transection (to remove the hypothalamus) significantly reduced thoracic (t) SNA."
"In contrast, in DH rats, Losartan, followed by pre-collicular and pontine transections, failed to reduce tSNA, whereas transection at the medulla-spinal cord junction massively reduced tSNA. In DH...
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Source: Gene Therapy Weekly (2011-10-27)
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