Small Interference RNAs (siRNAs)
New Small Interference RNAs (siRNAs) Study Results from Chinese Academy of Sciences Described
Published in Gene Therapy Weekly, November 24th, 2011
2011 NOV 24 -- In this recent study, researchers in Guangdong, People's Republic of China conducted a study "To explore the effects of siRNA silencing of PIK3CA on proliferation, migration and invasion of gastric cancer cells and to investigate the underlying mechanisms. The mutation of PIK3CA in exons 9 and 20 of gastric cancer cell lines HGC-27, SGC-7901, BGC-823, MGC-803 and MKN-45 was screened by polymerase chain reaction (PCR) followed by sequencing."
"BGC-823 cells harboring no mutations in either of the exons, and HGC-27 cells containing PIK3CA mutations were employed in the current study. siRNA targeting PIK3CA was chemically synthesized and was...
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Source: Gene Therapy Weekly (2011-11-24)
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