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Gene Therapy

Data on Gene Therapy Detailed by Researchers at Karolinska University Hospital

Published in Gene Therapy Weekly, November 24th, 2011

2011 NOV 24 -- Researchers detail in "HDAC inhibitor 4-phenylbutyrate preserves immature phenotype of human embryonic midbrain stem cells: implications for the involvement of DNA methyltransferase," new data in Gene Therapy. According to the authors of a study from Solna, Sweden, "Cell replacement and gene therapy using neural stem cells (NSCs) have been widely touted as a promising treatment for CNS diseases including brain tumors. Histone deacetylase (HDAC) inhibitors have been used to explore mechanisms behind the lineage-specific differentiation of NSCs and as modulators of gene therapy."

"We have used the human embryonic midbrain stem cell line NGC-407...

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