Gene Therapy
Study Data from University of California Update Understanding of Gene Therapy
Published in Gene Therapy Weekly, December 8th, 2011
2011 DEC 8 -- According to the authors of recent research from Sacramento, California, "A key mechanism for mesenchymal stem cells/bone marrow stromal cells (MSCs) to promote tissue repair is by secretion of soluble growth factors (GFs). Therefore, clinical application could be optimized by a combination of cell and gene therapies, where MSCs are genetically modified to express higher levels of a specific factor."
"However, it remains unknown how this overexpression may alter the fate of the MSCs. Here, we show effects of overexpressing the growth factors, such as basic fibroblast growth factor (bFGF), platelet derived growth factor B (PDGF-BB),...
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Source: Gene Therapy Weekly (2011-12-08)
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