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Gene Therapy

The art of stabilizing entangled spaghetti-like materials

Published in Gene Therapy Weekly, December 15th, 2011

2011 DEC 15 -- Gene therapy can only be effective if delivered by a stable complex molecule. Now, scientists have determined the conditions that would stabilise complex molecular structures that are subject to inherent attractions and repulsions triggered by electric charges at the surfaces of the molecules, in a study about to be published in EPJ E', by Valentina Mengarelli and her colleagues from the Solid State Physics Laboratory at the Paris-Sud University in Orsay, France, in collaboration with Paris 7 and Evry Universities scientists.

The authors studied soluble complexes made of negatively charged DNA or another negatively charged polymer -...

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