New Enzyme Precursors Study Findings Have Been Reported by Researchers at Northwestern University

2011 DEC 15 -- New research, "Development of novel therapeutics targeting the urokinase plasminogen activator receptor (uPAR) and their translation toward the clinic," is the subject of a report. "The urokinase plasminogen activator receptor (uPAR) mediates cell motility and tissue remodeling. Although uPAR may be expressed transiently in many tissues during development and wound healing, its constitutive expression appears to be associated with several pathological conditions, including cancer. uPAR expression has been demonstrated in most solid tumors and several hematologic malignancies including multiple myeloma and acute leukemias.Unlike many tumor antigens, uPAR is...

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