Gene Therapy
Findings from INSERM in Gene Therapy Reported
Published in Gene Therapy Weekly, December 22nd, 2011
2011 DEC 22 -- Research findings, "Biodistribution and shedding of AAV vectors," are discussed in a new report. According to the authors of a study from Nantes, France, "Determining the AAV vector biodistribution and shedding is central for the safety assessment of proposed early-phase clinical trials. It is especially crucial in the case of AAV vectors since they are injected directly in situ with no possibility of an intermediate ex vivo step, such as in retroviral-mediated approaches."
"This sole administration mode, the high capsid diversity (natural and chimeric), the various routes of delivery (e.g., intramuscular, intravenous, intra-arterial, and...
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Source: Gene Therapy Weekly (2011-12-22)
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