Gene Therapy
Recent Findings in Gene Therapy Described by Researchers from San Raffaele Telethon Institute for Gene Therapy
Published in Gene Therapy Weekly, December 29th, 2011
2011 DEC 29 -- A report, "Integration profile of retroviral vector in gene therapy treated patients is cell-specific according to gene expression and chromatin conformation of target cell," is newly published data in Embo Molecular Medicine. "The analysis of genomic distribution of retroviral vectors is a powerful tool to monitor 'vector-on-host' effects in gene therapy (GT) trials but also provides crucial information about 'host-on-vector' influences based on the target cell genetic and epigenetic state. We had the unique occasion to compare the insertional profile of the same therapeutic moloney murine leukemia virus (MLV) vector in the context of the adenosine...
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Source: Gene Therapy Weekly (2011-12-29)
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