Apoptosis

Data on Apoptosis Described by Researchers at South China Normal University

Published in Gene Therapy Weekly, January 19th, 2012

2012 JAN 19 -- A new study, "Cell death via mitochondrial apoptotic pathway due to activation of Bax by lysosomal photodamage," is now available. "Lysosomal photosensitizers have been used in photodynamic therapy. The combination of such photosensitizers and light causes lysosomal photodamage, inducing cell death," scientists in Guangzhou, People's Republic of China report.

"Lysosomal disruption can lead to apoptosis but its signaling pathways remain to be elucidated. In this study, N-aspartyl chlorin e6 (NPe6), an effective photosensitizer that preferentially accumulates in lysosomes, was used to study the mechanism of apoptosis caused by lysosomal...

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Source: Gene Therapy Weekly (2012-01-19)

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