Lymphoma
New Lymphoma Research from Jichi Medical University Outlined
Published in Gene Therapy Weekly, February 2nd, 2012
2012 FEB 2 -- According to the authors of recent research published in the journal Blood, "Many transformed lymphoma cells show immune-phenotypes resembling the corresponding normal lymphocytes; thus, they provide a guide for proper diagnosis and present promising routes to improve their pathophysiologic understanding and to identify novel therapeutic targets. However, the underlying molecular mechanism(s) of these aberrant immunephenotypes is largely unknown."
"Here, we report that microRNA-135b (miR-135b) mediates nucleophosmin-anaplastic lymphoma kinase (NPM-ALK)-driven oncogenicity and empowers IL-17-producing immunophenotype in anaplastic large...
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Source: Gene Therapy Weekly (2012-02-02)
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