Peptides and Proteins
Findings from University of Alberta Provide New Insights into Peptides and Proteins
Published in Gene Therapy Weekly, February 2nd, 2012
2012 FEB 2 -- Data detailed in "Actions of ß-amyloid protein on human neurons are expressed through the amylin receptor" have been presented. According to the authors of a study from Edmonton, Canada, "Disruption of neurotoxic effects of amyloid ß protein (Aß) is one of the major, but as yet elusive, goals in the treatment of Alzheimer's disease (AD). The amylin receptor, activated by a pancreatic polypeptide isolated from diabetic patients, is a putative target for the actions of Aß in the brain."
"Here we show that in primary cultures of human fetal neurons (HFNs), AC253, an amylin receptor antagonist, blocks electrophysiological...
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Source: Gene Therapy Weekly (2012-02-02)
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