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Small Interference RNAs (siRNAs)

Research in the Area of Small Interference RNAs (siRNAs) Reported from Kanazawa University

Published in Gene Therapy Weekly, February 16th, 2012

2012 FEB 16 -- In this recent study, researchers in Ishikawa, Japan conducted a study "To investigate the effect of dienogest on the expression of Toll-like receptor (TLR) 4 in human endometrial epithelial cells. Prospective basic research study."

"Pharmaceutical research center. None. Not applicable. TLR4 in the immortalized progesterone receptor-expressing human endometrial epithelial cell line, EM-PR, was activated with lipopolysaccharide and high-mobility group box 1 (LPS/HMGB1) in the presence or absence of the synthetic progestin dienogest or endogenous progesterone. The production of interleukin (IL)-8, IL-6, and monocyte chemoattractant protein...

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