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Cancer Gene Therapy

Research Conducted at Union Hospital Has Provided New Information about Cancer Gene Therapy

Published in Gene Therapy Weekly, February 16th, 2012

2012 FEB 16 -- New research, "SNCG gene silencing in gallbladder cancer cells inhibits key tumorigenic activities," is the subject of a report. According to the authors of a study from Fuzhou, People's Republic of China, "We recently determined that synuclein-gamma (SNCG) is highly expressed in human gallbladder cancer (GBC), and its abnormal expression is associated with tumor aggressiveness. To investigate the effects of SNCG gene silencing on the tumorigenic profiles of the GBC cell line, NOZ, short-hairpin RNA (shRNA) interference was employed."

"Specifically, the SNCG transcript was targeted by SNCG-shRNA lentiviral particles designed to silence SNCG...

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