Published in Gene Therapy Weekly, February 23rd, 2012
"The OUR was determined on-line by the dynamic method, providing good information of the process evolution. OUR enabled cell activity monitoring, facilitating as well the determination of the feeding rate in perfusion cultures and when to infect the culture. Batch cultures were used to validate the monitoring methodology. A cell density of 10 x 10(5) cell/mL was infected, producing 1.3 x 10(9) infectious viral...
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