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DNA Research

Studies from Nagoya University Further Understanding of DNA Research

Published in Gene Therapy Weekly, February 23rd, 2012

2012 FEB 23 -- "Understanding the mechanisms of DNA compaction is becoming increasingly important for gene therapy and nanotechnology DNA applications. The kinetics of the compaction velocity of single DNA molecules was studied using two non-protein condensation systems, poly(ethylene glycol) (PEG) with Mg2+ for the polymer-salt-induced condensation system and spermine for the polyamine condensation system," researchers in Nagoya, Japan report.

"The compaction velocities of single tandem lambda-DNA molecules were measured at various PEG and spermine concentrations by video fluorescent microscopy. Single DNA molecules were observed using a molecular...

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