Gene Therapy
Research Conducted at Stanford University Has Updated Our Knowledge about Gene Therapy
Published in Gene Therapy Weekly, March 1st, 2012
2012 MAR 1 -- Data detailed in "Quantitative assessment of Ras over-expression via shotgun deployment of vectors utilizing synthetic promoters" have been presented. "We sought to characterize and compare wild-type and oncogenic Ras over-expression. Because different levels of Ras over-expression can have different effects on cell phenotype, it was important to evaluate a wide range of expression," scientists in Stanford, California report.
"Different expression levels were achieved by using retroviral vectors equipped with different strength promoters. Cells were 'shotgun' transduced with a mixture of these vectors to generate heterogeneous populations...
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Source: Gene Therapy Weekly (2012-03-01)
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