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Ovarian Cancer

Research in the Area of Ovarian Cancer Reported from Medical College

Published in Gene Therapy Weekly, March 1st, 2012

2012 MAR 1 -- Research findings, "Autocrine production of interleukin-8 confers cisplatin and paclitaxel resistance in ovarian cancer cells," are discussed in a new report. "It has been widely reported that interleukin-8 (IL-8) is overexpressed in ovarian cyst fluid, ascites, serum, and tumor tissue from ovarian cancer (OVCA) patients, and elevated IL-8 expression correlates with a poor final outcome and chemosensitivity. However, the role of IL-8 expression in the acquisition of the chemoresistance phenotype and the underlining mechanisms of drug resistance in OVCA cells are not yet fully understood," scientists writing in the journal Cytokine report.

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