Small Interference RNAs (siRNAs)
Studies from Seoul National University Further Understanding of Small Interference RNAs (siRNAs)
Published in Gene Therapy Weekly, March 8th, 2012
2012 MAR 8 -- Investigators discuss in "Cationic solid lipid nanoparticles for co-delivery of paclitaxel and siRNA" new findings in Small Interference RNAs (siRNAs). "In this study, we formulated cationic solid lipid nanoparticles (cSLN) for co-delivery of paclitaxel (PTX) and siRNA. 1,2-Dioleoyl-sn-glycero-3-ethylphosphocholine-based cSLN were prepared by emulsification solidification methods. PTX-loaded cSLN (PcSLN) were characterized by zeta potential and gel retardation of complexes with small interfering RNA (siRNA)," investigators in Seoul, South Korea report.
"The sizes of PcSLN did not significantly differ from those of empty cSLN without PTX...
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Source: Gene Therapy Weekly (2012-03-08)
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