Nanomedicine
New Nanomedicine Study Findings Have Been Reported by Investigators at University of Medicine and Dentistry of New Jersey (UMDNJ)
Published in Gene Therapy Weekly, March 22nd, 2012
2012 MAR 22 -- In this recently published study, investigators in New Brunswick, New Jersey conducted a study "To develop an approach for the effective treatment of ovarian tumor, prevention of metastases and limitation of side effects. In order to combine chemotherapy with genotherapy, we constructed a nanoscale-based tumor-targeted system containing two anticancer drugs, two antisense oligonucleotides (suppressors of cellular resistance) and a ligand specific to receptors overexpressed in cancer cells."
"The system was tested in a mouse metastatic xenograft model using tumor isolates from patients with ovarian carcinoma. Treatment with the proposed...
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Source: Gene Therapy Weekly (2012-03-22)
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