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Gene Therapy

Studies from University of California Yield New Data on Gene Therapy

Published in Gene Therapy Weekly, March 29th, 2012

2012 MAR 29 -- A new study, "Utilizing cell-matrix interactions to modulate gene transfer to stem cells inside hyaluronic acid hydrogels," is now available. "The effective delivery of DNA locally would increase the applicability of gene therapy in tissue regeneration, where diseased tissue is to be repaired in situ. One promising approach is to use hydrogel scaffolds to encapsulate and deliver plasmid DNA in the form of nanoparticles to the diseased tissue, so that cells infiltrating the scaffold are transfected to induce regeneration," investigators in Los Angeles, California report.

"This study focuses on the design of a DNA nanoparticle-loaded hydrogel...

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