Antisense Technology

Reports from Tel Aviv University Add New Data to Research in Antisense Technology

Published in Gene Therapy Weekly, April 5th, 2012

2012 APR 5 -- According to the authors of recent research from Tel Aviv, Israel, "Corticotrophin-releasing hormone (CRH) plays a key role in the adjustment of neuroendocrine and behavioural adaptations to stress. Dysregulation in CRH systems has been implicated in a variety of stress-related psychiatric disorders such as post-traumatic stress disorder (PTSD)."

"The present study examined the relationship between stress-induced PTSD-like behavioural response patterns and levels of CRH, CRH receptor (CHR-R)1 and phosphorylated extracellular signal-regulated kinase (pERK1/2) in the rat hippocampus subregions. The effects of pharmacological manipulations on...

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Source: Gene Therapy Weekly (2012-04-05)

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