Anaphylaxis
Reports from Tohoku University Highlight Recent Research in Anaphylaxis
Published in Gene Therapy Weekly, April 5th, 2012
2012 APR 5 -- New investigation results, "Stimulation of Ly-6G on neutrophils in LPS-primed mice induces platelet-activating factor (PAF)-mediated anaphylaxis-like shock," are detailed in a study published in Journal of Leukocyte Biology. According to the authors of recent research from Sendai, Japan, "Previously, two anti-Ly-6G mAb-RB6-8C5 and 1A8-have been used to deplete neutrophils in mice and to clarify their involvement in immune responses. During the course of experiments on neutrophil depletion, we noticed that i.v. injection of RB6-8C5 or 1A8 induced anaphylaxis-like shock in mice pretreated i.v. with LPS."
"Signs of shock, such as...
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Source: Gene Therapy Weekly (2012-04-05)
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