Cardiology
Data on Cardiology Detailed by Researchers at Autonomous University
Published in Gene Therapy Weekly, April 5th, 2012
2012 APR 5 -- Data detailed in "Protein Kinase C (PKC)'-mediated Gaq Stimulation of ERK5 Protein Pathway in Cardiomyocytes and Cardiac Fibroblasts" have been presented. According to the authors of recent research from Madrid, Spain, "Gq-coupled G protein-coupled receptors (GPCRs) mediate the actions of a variety of messengers that are key regulators of cardiovascular function. Enhanced Ga(q)-mediated signaling plays an important role in cardiac hypertrophy and in the transition to heart failure."
"We have recently described that Ga(q) acts as an adaptor protein that facilitates PKC'-mediated activation of ERK5 in epithelial cells. Because the ERK5 cascade...
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Source: Gene Therapy Weekly (2012-04-05)
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