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New Gene Therapy Study Findings Recently Were Reported by Researchers at Mayo Clinic

Published in Gene Therapy Weekly, April 19th, 2012

2012 APR 19 -- "Oncolytic measles virus (MV) encoding the human thyroidal sodium iodide symporter (MV-NIS) has proved to be safe after intraperitoneal or intravenous administration in patients with ovarian cancer or multiple myeloma, respectively, but it has not yet been administered through intratumoral injection in humans. Squamous cell carcinoma (SCC) of the head and neck (SCCHN) usually is locally invasive and spreads to the cervical lymph nodes, which are suitable for the intratumoral administration of oncolytic viruses," investigators in Rochester, Minnesota report.

"To test whether oncolytic MV is an effective treatment for SCCHN, we used oncolytic...

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