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Gene Therapy

Studies from National Institute of Mental Health Update Current Data on Gene Therapy

Published in Gene Therapy Weekly, April 19th, 2012

2012 APR 19 -- According to the authors of recent research published in the Journal of Gene Medicine, "Background A fundamental obstacle to using retroviral-mediated gene transfer (GT) to treat human diseases is the relatively low transduction levels that have been achieved in clinically relevant human cells. We previously showed that performing GT in utero overcomes this obstacle and results in significant levels of transduction within multiple fetal organs, with different tissues exhibiting optimal transduction at different developmental stages."

"We undertook the present study aiming to elucidate the mechanism for this age-dependent transduction,...

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