Gene Therapy
Research Data from Spanish National Research Council (CSIC) Update Understanding of Gene Therapy
Published in Gene Therapy Weekly, May 17th, 2012
2012 MAY 17 -- According to the authors of recent research from Granada, Spain, "This work aimed to develop a new therapeutic approach to increase the efficacy of 5-fluorouracil (5-FU) in the treatment of advanced or recurrent colon cancer. 5-FU-loaded biodegradable poly(e-caprolactone) nanoparticles (PCL NPs) were combined with the cytotoxic suicide gene E (combined therapy). The SW480 human cancer cell line was used to assay the combined therapeutic strategy."
"This cell line was established from a primary adenocarcinoma of the colon and is characterized by an intrinsically high resistance to apoptosis that correlates with its resistance to 5-FU. 5-FU was...
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Source: Gene Therapy Weekly (2012-05-17)
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