Genaera Corp

Study: Increased IL-9 related to early asthma clinical changes

Published in Genetics and Environmental Business Week, April 15th, 2004

Genaera Corp. (GENR) announced the publication of a study demonstrating a correlation of increased interleukin-9 (IL-9) expression with early changes that precede asthma, known as bronchial hyperresponsiveness (BHR) and bronchial eosinophilia.

BHR is found in virtually all asthmatics and is an exaggerated narrowing of the airways in response to the standardized inhalation of a triggering substance such as histamine or methacholine. Asymptomatic BHR is thought to be genetically mediated and precede the development of asthma. In the study, two groups of patients with BHR showed an increased expression in IL-9 protein and mRNA as well as an increase in the expression of...

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Source: Genetics and Environmental Business Week (2004-04-15)

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