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Medical University of South Carolina

Recent findings illuminate research in cardiology

Published in Genetics and Environmental Business Week, December 1st, 2005

Investigators in the United States and Germany have published new cardiology data.

Study 1: Knockout of the neural and heart expressed gene HF-1b results in apical deficits of ventricular structure and activation.

Investigators in the United States report, "Knockout of the neural and cardiac expressed transcription factor HF-1b causes electrophysiological abnormalities including fatal ventricular arrhythmias that occur with increasing frequency around the 4th week of postnatal life. [Our] study addresses factors that may contribute to conduction disturbance in the ventricle of the HF-1b knockout mouse."

K.W....

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