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Genetics and Environmental Business Week

Susan Hasty, Publisher

Table of Contents . . . December 8th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Genetics and Environmental Business Week | Other Publications

Cepheid - Genetic assessment company reports third-quarter 2005 results

Human Genome Sciences, Inc. - Genomics firm calls for all remaining outstanding subordinated notes due 2007

Targeted Genetics Corporation - Biotechnology company reports third quarter net loss of $5.7 million

Transgenomic Inc. - Provider of research tools closes announced private placement of common stock

ZymoGenetics, Inc. - Company developing therapeutic proteins reports net loss of $20.4 million

Aarhus University Hospital - Mutations in arginine vasopressin gene indicate genotype-phenotype correlation in FNDI

Affymetrix, Inc. - Partnership aims to discover, validate gene expression signatures for common childhood cancers

Auburn University - Molecular mechanisms of MC3R and MC4R dysfunction in early onset obesity are reviewed

Baylor College of Medicine, Houston - Hormone modifications may improve therapeutic potential for diabetes management

Cedars-Sinai Medical Center, Los Angeles - Studies show apo A-I Milano gene transfer cuts atherosclerotic plaque

Centocor Inc. - Genetic instability in cancer discussed

Chonnam National University, Jeollanamdo - Researchers' work adds to ovarian cancer body of knowledge

Cleveland Clinic Foundation - Airway epithelial cells express mRNA and protein for soluble and membrane-bound stem cell factor

Columbia University, New York - Study indicates weight gain in perimenopausal women increases breast cancer risk

Duke University Medical Center, Durham - Recommendations for hormone replacement therapy should not increase cancer risk

Duke University, Durham -  C. neoformans used as molecular fungal pathogenesis model to identify drug targets

DxS Ltd - Personalized medicine company launches consultancy and training service

Federal University of Bahia, Sal Paulo - Hepatitis B and D viruses are prevalent in the western Brazilian Amazon

Fred Hutchinson Cancer Research Center, Seattle - Diet and weight loss do not affect cell proliferation biomarkers in Barrett esophagus

Fred Hutchinson Cancer Research Center, Seattle - Genetic sequencing uncovers new bacterial species associated with vaginosis

Georgetown University Medical Center, Washington, DC - Nanodelivery systems target primary and metastatic tumors

Georgetown University, Washington, DC - Tumor necrosis factor and HCV have key roles in hepatocellular carcinoma

Gothenburg University - Novel method of genotyping of hepatitis C virus by Taqman real-time PCR chronicled

Harvard School of Public Health - Research finds cigarette manufacturers target youth market with candy flavored cigarette brands

Harvard University - Polymorphisms in vitamin D receptor may mediate breast cancer risk

Harvard University - Tetraploidy promotes tumorigenesis in p53-null cells

Healthcare Access - The private health sector in India is burgeoning but at the cost of public healthcare

Healthcare Costs - Group says preferred drug lists interfere with successful asthma control

Hospital de la Santa Creu i Sant Pau, Barcelona - Inflammatory properties of LDL- in diabetics are related to increased PAF-AH activity

Hospital for Sick Children, Toronto - Transporter ATPase gene (ATP13A4) may have a role in speech-language disorder

Howard Hughes Medical Institute - Loss of fear factor makes a timid mouse bold

Illumina, Inc. - Large-scale genotyping to be performed for colorectal cancer study

Imperial College School of Medicine, London - Stable inhibition of hepatitis B virus proteins is achieved by viral vector RNA

Indiana University - Gene thought to influence perception gene was important in human evolution, scientists say

Information Technology - Carolinas HealthCare System contracts with Cerner

Inha University Hospital, Inchon - WHO class-specific equations using height2 was developed for predicting body weight

Institute of Psychiatry, London - Brain abnormalities in schizophrenia are imaged

Instituto de Salud Carlos III, Madrid - Drug-resistant HIV-1 mutations in the former Soviet Union are identified

Italy Istituto Nazionale Riposo e Cura Anziani, Ancona - 1267 HSP70-2 polymorphism may indicate carotid plaque rupture and cerebral ischemia risk

Jennerex Biotherapeutics - Oncolytic vaccinia viruses show promise in treatment of cancer

Joslin Diabetes Center, Boston - HMW adiponectin is not linked to endothelium-dependent vasodilation in diabetic offspring

Kansai Medical University, Osaka - New findings in the area of skin cancer described

Karolinska Institute - Study suggests intake of high-fat dairy foods may reduce colorectal cancer risk

Kyushu University, Fukuoka - Adequate folate intake conferred protection from colorectal cancer

Laboratory of Oral Microbiology, Bergen - Dental plaque considered respiratory pathogen for those hospitalized with chronic lung disease

London School of Hygiene & Tropical Medicine - Early childhood BMI does not drive early menarche and continued obesity

Louisiana State University - Gene therapy may purge leukemia cells from hematopoietic progenitor cells

Memorail Sloan-Kettering Cancer Center - HSV-based gene therapy enhances mitomycin efficacy in bladder cell carcinoma

Montgomery VA Medical Center - Fem1b inactivation leads to abnormal glucose homeostasis and pancreatic islet function

Nagoya University Graduate School of Medicine - XRCC1 Arg399Gln polymorphism may be important risk factor for cervical cancer

Nara Institute of Science & Technology - A molecular model for axon guidance is based on cross talk between Rho GTPases

Osaka University - Necdin gene disruption diminishes TrkA signaling for sensory neuron survival

Princeton University - Alternative splicing modifies components of signaling pathways important for stem cell function

Solexa, Inc. - Company focused on genetic analysis systems adds two patents to IP portfolio

Tampere University Hospital - BMPR2 mutations have short lifetime expectancy in primary pulmonary hypertension

Targeted Genetics Corporation - Michael S. Perry, DVM, PhD, named to board of biotechnology company

Technion-Israel Institute of Technology, Haifa - Antisense knockdown of isoquinoline binding protein achieved in C6 glioma cell line

Tulane University, New Orleans - Researchers detail new studies and findings in the area of neurology

U.S. Army Medical Research Institute of Infectious Diseases - Real-time PCR targets a unique chromosomal sequence of Yersinia pestis

Ultrasound & New Modalities Research - Gas-filled microparticles and sonoporation are effective against tumors

Umea University Hospital - PAI-1 4G/5G polymorphism is associated with increased risk of ischemic stroke

University of Auckland - Flexible medium-throughput strategy for protein production is developed

University of Auckland - MC4R gene tissue specific expression requires one kb of the 5' flanking sequence

University of Bretagne Occidentale - Serial replication slippage can cause complex gene rearrangements

University of British Columbia - Researchers publish new studies and findings in the area of ischemia

University of Cambridge - Sushi-class retrotransposon-derived genes have role in genomic imprinting

University of Cologne - Nidogen ablation causes basement membrane defects and perinatal lethality

University of Colorado - Increased EGFR gene copy number linked to increased gefitinib sensitivity in lung cancer patients

University of Ferrara - Cyclooxygenase-2 inhibitors used to reverse chemoresistance phenotype in medullary thyroid carcinoma

University of Florida - Scientists engineer mice for Alzheimer disease therapy study

University of Kuopio - VP22 does not significantly enhance enzyme prodrug cancer gene therapy

University of London Imperial College - Chronic fatigue syndrome is associated with human leukocyte antigen alleles

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