Bulgarian Academy of Sciences, Sofia
Report presents map of PSMA epitopes recognized by antibodies induced by gene-based vaccines
Published in Genetics and Environmental Business Week, February 2nd, 2006
"A possible new target for immunotherapy is the prostate-specific membrane antigen (PSMA). The aim of the present study was to define potential PSMA epitopes for antibody binding using sera from patients immunized with gene-based anti-PSMA vaccines," researchers in Bulgaria report.
"Sera from prostate cancer patients, immunized repeatedly with plasmid and adenoviral vectors, each encoding for the extracellular portion of human PSMA, were tested for anti-PSMA antibodies by Western...
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