University of Minnesota
Adenoviral-mediated gene therapy elevates activated partial thromboplastin time in prostate cancer
Published in Genetics and Environmental Business Week, February 2nd, 2006
B.S. Malaeb and colleagues, University of Minnesota, wrote that the purpose of the study was "to evaluate the cause and significance of elevated aPTT in a group of patients who received a first-generation adenoviral vector (Ad-OC-TK) delivering a toxic gene to prostate cancer cells as part of a Phase I clinical trial at the University of Virginia."
"Eleven subjects were injected intratumorally to metastatic lesions of prostate cancer in the prostatic fossa, retroperitoneal lymph nodes, or...
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