Aichi Cancer Center, Aichi, Japan

Findings from Japan advance knowledge in lung cancer research

Published in Genetics and Environmental Business Week, October 19th, 2006

Reports from Japan highlight recent research in lung cancer.

Study 1: Common lung cancer mutations are sometimes joined by second mutations.

According to a study from Japan, "Activating mutations of EGFR are found frequently in a subgroup of patients with non-small cell lung cancer (NSCLC) and are highly correlated with the response to gefitinib and erlotinib. In the present study, we searched for mutations of epidermal growth factor receptor (EGFR), HER2 and KRAS in 264 resected primary NSCLC from Japanese patients and determined whether there is a correlation between genetic alterations of these genes and clinicopathological factors, together with...

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Source: Genetics and Environmental Business Week (2006-10-19)

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