Institute for Clinical & Experimental Medicine, Czech Republic
New findings from the Czech Republic, Japan and United Kingdom in the area of angiology described
Published in Genetics and Environmental Business Week, October 19th, 2006
Study 1: IL-10 and TNF-beta gene polymorphisms have no major influence on lactate levels after cardiac surgery.
"Lactate levels after cardiac surgery are influenced by different proinflammatory (TNF, IL-6, IL-8) and anti-inflammatory (IL-10) cytokines. The goal of the study was to determine the relationship between polymorphism in the IL-10 (-1082G/A) and TNF-beta (+252G/A) genes and lactate levels in patients after cardiac surgery. We performed a prospective observational study in 168 consecutive adult patients without left ventricle dysfunction...
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