Breast Cancer

Scientists from University of California, U.S., target breast cancer

Published in Genetics and Environmental Business Week, November 23rd, 2006

New breast cancer data have been reported by researchers from University of California, U.S.

Study 1: 15-hydroxyprostaglandin dehydrogenase (15-PGDH) might be a tumor suppressor gene in breast cancer.

According to a study from the United States, "Prostaglandin E-2 plays a growth-stimulatory role in breast cancer, and the rate-limiting enzyme in its synthesis, cyclooxygenase-2, is often overexpressed in these cancers. Little is known about the role of the key prostaglandin catabolic enzyme 15-PGDH in breast cancer pathogenesis."

"Using a pharmacologically based screen for epigenetically silenced genes, we found low levels of...

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Source: Genetics and Environmental Business Week (2006-11-23)

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