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Genetics & Genomics

Researchers from University of Pennsylvania detail new studies and findings in the area of genetics & genomics

Published in Genetics and Environmental Business Week, February 22nd, 2007

Research findings, "Wnt-beta-catenin signaling initiates taste papilla development," are discussed in a new report. "Fungiform taste papillae form a regular array on the dorsal tongue. Taste buds arise from papilla epithelium and, unusually for epithelial derivatives, synapse with neurons, release neurotransmitters and generate receptor and action potentials," researchers in the United States report.

"Despite the importance of taste as one of our five senses, genetic analyses of taste papilla and bud development are lacking. We demonstrate that Wnt-beta-catenin signaling is activated in developing fungiform placodes and taste bud cells. A dominant stabilizing mutation...

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