Gene Therapy
New gene therapy study results from University of California, Department of Animal Science described
Published in Genetics and Environmental Business Week, April 5th, 2007
Research findings, "The effect of coating single- and double-stranded DNA with the recombinase A protein of Escherichia coli on transgene integration in mice," are discussed in a new report. "Embryo survival and transgene integration rates are two major factors that influence the efficiency of transgenic animal production by pronuclear microinjection. Recombinase A protein-coated transgenes were compared for transgene integration and embryo survival with their non-coated counterparts in both single-and double-stranded forms," investigators in the United States report.
"Murine zygotes were microinjected with a large 30 kb alpha(S1)-casein/human lysozyme DNA construct and...
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