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Genetics & Environmental Business Week

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Anatomy



National Yang-Ming University, Institute of Anatomy and Cell Biology describes research in anatomy



November 22nd, 2007

Fresh data on anatomy are presented in the report 'The CBF1-independent Notch1 signal pathway activates human c-myc expression partially via transcription factor YY1.' According to recent research from Taipei, Taiwan, "Transcription factor Ying Yang 1 (YY1) indirectly regulates the C promoter-binding factor 1 (CBF1)-dependent Notch1 signaling via direct interaction with the Notch1 receptor intracellular domain (N1IC) on CBF1-response elements. To evaluate the possibility that the N1IC might modulate the gene expression of YY1 target genes through associating with YY1 on the YY1-response elements, we herein investigated the effect of Notch1 signaling on the expression of YY1 target...


Source: Genetics & Environmental Business Week (2007-11-22)

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