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Genetics & Environmental Business Week

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Angiotensins



Research from University of Texas, Health Science Center has provided new information about angiotensins



November 22nd, 2007

New research, 'MYH11 mutations result in a distinct vascular pathology driven by insulin-like growth factor 1 and angiotensin II,' is the subject of a report. "Non-syndromic thoracic aortic aneurysms and dissections (TAADs) are inherited in an autosomal dominant manner in approximately 20% of cases. Familial TAAD is genetically heterogeneous and four loci have been mapped for this disease to date, including a locus at 16p for TAAD associated with patent ductus arteriosus (PDA)," scientists in the United States report.

"The defective gene at the 16p locus has recently been identified as the smooth muscle cell (SMC)-specific myosin heavy chain gene (MYH11). On sequencing...


Source: Genetics & Environmental Business Week (2007-11-22)

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