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Antisense Technology
Research from Kyushu University, Medical Institute of Bioregulation in the area of antisense technology published
November 22nd, 2007
Current study results from the report, 'Ifi202, an IFN-inducible candidate gene for lupus susceptibility in NZB/W F1 mice, is a positive regulator for NF-kappaB activation in dendritic cells,' have been published. "Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the presence of autoantibodies and lupus nephritis. The [New Zealand black (NZB) x New Zealand white (NZW)]F1 (BWF1) mouse has been recognized as an important animal model of human SLE," researchers in Fukuoka, Japan report. "The T(h)1-prone phenotype of BWF1 mice has been shown to contribute to the development of the lupus. However, the molecular basis for T(h)1 skewing in BWF1 mice...
Source: Genetics & Environmental Business Week (2007-11-22)
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