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Genetics & Environmental Business Week

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Antisense Technology



Research from M. Roccaro and co-researchers in the area of antisense technology published



November 22nd, 2007

"ROSINA (RSI) was isolated as a DNA binding factor able to bind to the CArG-box present in the promoter of the MADS-box gene DEFICIENS of Antirrhinum majus. The mosaic nature of RSI and its multi-copy presence in the A. majus genome indicated that RSI could be a part of a mobile genetic element," investigators in Cologne, Germany report.

"Here we show that RSI is a part of a CACTA transposable element system of A. majus, named TamRSI, which has evolved and is still evolving within the terminal inverted repeats (TIRs) of this CACTA transposon. Interestingly, RSI is always found in opposite orientation with respect to the transcription of a second gene present within the...


Source: Genetics & Environmental Business Week (2007-11-22)

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