Genetics & Environmental Business Week
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Antisense Technology
Researchers from University of Miami, Department of Pathology discuss findings in antisense technology
November 22nd, 2007
Researchers detail in 'Downregulation of the 18-kDa translocator protein: effects on the ammonia-induced mitochondrial permeability transition and cell swelling in cultured astrocytes,' new data in antisense technology. "Hepatic encephalopathy (HE) is a major neurological complication in patients with severe liver disease. While the pathogenesis of HE is unclear, elevated blood and brain ammonia levels are believed to be major etiological factors, and astrocytes appear to be the primary target of its toxicity," scientists in the United States report. "A notable feature of ammonia neurotoxicity is an upregulation of the 18-kDa translocator protein (TSPO) (formerly...
Source: Genetics & Environmental Business Week (2007-11-22)
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