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Antisense Technology
Studies from University of Tokushima, Institute for Genome Research add new findings in the area of antisense technology
November 22nd, 2007
A report, 'Gene silencing mechanisms mediated by Aubergine piRNA complexes in Drosophila male gonad,' is newly published data in RNA. According to a study from Tokushima, Japan, "Genetic studies have shown that Aubergine (Aub), one of the Piwi subfamily of Argonautes in Drosophila, is essential for germ cell formation and maintaining fertility. aub mutations lead to the accumulation of retrotransposons in ovaries and testes, and Stellate transcripts in testes. Aub in ovaries associates with a variety of Piwi-interacting RNAs (piRNAs) derived from repetitive intergenic elements including retrotransposons." "Here we found that Aub in testes also associates with...
Source: Genetics & Environmental Business Week (2007-11-22)
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