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Beckwith-Wiedemann Syndrome Genetics
New Beckwith-Wiedemann syndrome genetics research from University of Texas, M. D. Anderson Cancer Center outlined
November 22nd, 2007
Data detailed in 'A novel approach to detect parent-of-origin effects from pedigree data with application to Beckwith-Wiedemann syndrome' have been presented. "The parent-of-origin phenomenon in humans is now well recognized, and the deregulation of imprinted genes has been implicated in a number of human diseases. Recently, several linkage analysis methods have been developed to allow for parent-of-origin effects in the analysis of pedigree data," scientists in the United States report. "However, in general, one does not know a priori if disease-causing loci are imprinted or not. Linkage methods that allow for imprinting can lose power if there is no imprinting....
Source: Genetics & Environmental Business Week (2007-11-22)
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