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Gene Therapy

New gene therapy study results reported from Children's Hospital

Published in Genetics and Environmental Business Week, June 12th, 2008

A new study, 'Transcription repression and blocks in cell cycle progression in hypoplastic left heart syndrome,' is now available. "Hypoplastic left heart syndrome (HLHS) is characterized by abnormally developed atrial septum and a severe underdevelopment of the left side of the heart. Despite significant advances in its surgical management, little is known about the molecular abnormalities in this syndrome," scientists in the United States report.

"To gain molecular insights into HLHS, expression profiling by gene-chip microarray (Affymetrix U133 2.0) and by real-time RT-PCR was performed in the atrial septum of patients diagnosed with HLHS and compared with...

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