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Alzheimer Disease Genetics

Research on Alzheimer disease genetics reported by scientists at Pharmadyn Inc.

Published in Genetics and Environmental Business Week, October 2nd, 2008

Researchers detail in 'The many faces of amyloid beta in Alzheimer's disease,' new data in Alzheimer disease. According to a study from the United States, "The 'amyloid cascade hypothesis' links amyloid beta peptide (Abeta) with the pathological process of Alzheimer's disease (AD) and it still awaits universal acceptance. Amyloid precursor protein (APP), through the actions of the gamma-secretase complex, eventually becomes a different Abetaspecies."

"The various Abeta species have proven to be difficult to investigate under physiological conditions, and the species of Abeta responsible for neurotoxicity has yet to be unequivocally identified. The two important Abeta...

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