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Herpetic Keratitis

Research on herpetic keratitis discussed by scientists at Erasmus University

Published in Genetics and Environmental Business Week, October 2nd, 2008

According to a study from Netherlands, "Recent phylogenetic analyses on the herpes simplex virus type 1 (HSV-1) genes US4, encoding glycoprotein G (gG) and US7, encoding gI, of clinical HSV-1 isolates have led to the classification of HSV-1 into three genotypes, arbitrarily designated as A, B and C. The prevalence of the HSV-1 gG and gI genotypes and their potential disease association was determined in a large cohort of patients with herpetic keratitis (HK). Primary corneal HSV-1 isolates of 178 HK patients were genotyped by a PCR-based restriction fragment length polymorphism method targeting the viral genes US4 and US7."

"Genotype B was more frequently expressed by...

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