Non-Small Cell Lung Cancer

Research from Peking University yields new data on non-small cell lung cancer

Published in Genetics and Environmental Business Week, October 30th, 2008

" Delta DNMT3B (anew DNMT3B subfamily) expression is initiated through a novel promoter. We identified at least 7 transcription variants of Delta DNMT3B as a result of alternative pre-mRNA processing," scientists in Beijing, People's Republic of China report.

"The aim of this study was to detect the expression pattern of Delta DNMT3B variants in non-small cell lung cancer (NSCLC) and to explore the role of Delta DNMT3B variants in regulating the promoter-specific DNA methylation. Specific polymerase chain reaction (PCR) primer sets were designed to distinguish individual Delta DNMT3B variants according to their splicing patterns. The expressions of seven Delta DNMT3B...

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Source: Genetics and Environmental Business Week (2008-10-30)

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