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Gene Therapy

New gene therapy data have been reported by M. Suda and co-authors

Published in Genetics and Environmental Business Week, January 15th, 2009

According to recent research from Kyoto, Japan, "Expression at the mRNA level of six methionine biosynthesis genes in Corynebacterium glutamicum cells under oxygen-deprived conditions was repressed by supplementation of medium with methionine."

"The repression was not observed in a mutant deficient in the TetR-type transcriptional repressor McbR. Analysis of transcriptional start sites of the methionine biosynthesis genes confirmed that McbR binding motifs exist in the promoter regions of all genes repressed by methionine supplementation," wrote M. Suda and colleagues.

The researchers concluded: "Furthermore, electrophoretic mobility shift assays...

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