Genetics & Genomics

Reports summarize genetics & genomics research from University of Newcastle

Published in Genetics and Environmental Business Week, February 12th, 2009

According to recent research from Newcastle, Australia, "In the first article of this series, we reviewed the basic genetics concepts necessary to understand genetic association studies. In this second article, we enumerate the major issues in judging the validity of these studies, framed as critical appraisal questions."

"Was the disease phenotype properly defined and accurately recorded by someone blind to the genetic information' Have any potential differences between disease and nondisease groups, particularly ethnicity, been properly addressed' In genetic studies, one potential cause of spurious associations is differences between cases and controls in ethnicity, a...

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Source: Genetics and Environmental Business Week (2009-02-12)

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