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Angiotensins
New findings from Dalhousie University, Department of Anatomy & Neurobiology describe advances in angiotensins
June 4th, 2009
Data detailed in 'siRNA knocks down Hsp27 and increases angiotensin II-induced phosphorylated NF-kappaB p65 levels in aortic smooth muscle cells' have been presented. According to recent research from Halifax, Canada, "Angiotensin II (Ang II) induces the proinflammatory nuclear factor kappaB (NF-kappaB) in the vasculature. Heat shock and elevated levels of heat shock proteins (Hsps) decrease Ang II-induced NF-kappaB transcriptional activity and inflammation, but little is known about the role of specific Hsps." "Here we used small interfering RNA (siRNA) technology to examine the role of Hsp27 in the Ang II-induced NF-kappaB signaling pathway. Hsp27 siRNA was...
Source: Genetics & Environmental Business Week (2009-06-04)
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